Join us for the 25th Annual Harpoon 5-Miler on Saturday, May 16, 2026!

Registration will open on Tuesday, February 3, 2026.

The Harpoon 5-Miler in South Boston is not just a race—it’s a celebration of community, fitness, and hope. This annual event brings together runners, volunteers, and supporters from all walks of life to raise critical funds for two important charities: The Angel Fund for ALS Research 🧠💙 and the Peter Frates Family Foundation 🙌. Over the years, the race has raised over $3.1 million for the cure and care of ALS, making a real impact in the fight against this devastating disease. Participants will race through the vibrant streets of South Boston 🏃‍♂️🏃‍♀️, all while supporting groundbreaking ALS research and honoring the legacy of Peter Frates, whose battle with ALS inspired the global Ice Bucket Challenge 🧊💧.

With a beautiful course, a lively atmosphere, and the support of the Harpoon Brewery 🍺, the race is a must-do for anyone looking to challenge themselves, give back, and make a difference in the fight against ALS. After crossing the finish line, runners and volunteers can join the post-race celebration at Harpoon Brewery 🎉🍻, complete with refreshing beverages, a lively dance party with DJ Steve Greco 💃🎶, and more. It’s a day filled with purpose, energy, and camaraderie—all while supporting a cause that impacts countless lives. Whether you're running or volunteering, your participation helps bring us one step closer to a world without ALS 🌎❤️.