The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated $2,825,000 to the ACC, funding 63 research projects. 100% of all participant-raised dollars are donated directly to cancer research.

Our 2025 Fundraising Goal
$40,288
Raised of $300,000
Breakthroughs in Action

Thank You To Our Fundraisers!
Top Individuals
View AllLou Starzl
$6,110.00 raised of $10,000.00
Drew Costello
$5,050.00 raised of $500.00
Richard Adler
$2,550.00 raised
Steve Alperstein
$2,318.00 raised of $2,500.00
Chris Braudy
$1,761.53 raised of $2,500.00
Top Teams
View AllKeystone State Ride
$12,670.53 raised of $30,000.00
Mission Melanoma
$5,050.00 raised of $0.00
Team BC
$3,525.00 raised of $20,000.00
Beam of Life
$1,897.38 raised of $10,000.00
Donate To an Indvidual or a Team
Donate NowJoin Us to Make a Difference!
