The 19th Annual Run4Life 5K & 1-Mile Fun Run is back! Lace up with us to support the Prisma Health Cancer Institute and bring hope to our community.

Cancer doesn't take a day off, and neither do we! Every dollar raised stays local, helping those bravely battling cancer right here in Greenville.

Prices increase after November 1, 2026. Current prices are shown when you click Sign Up.

• Noon - 6:00 PM · Packet pickup at the YMCA

• 7:30 AM · Packet pickup opens and race day registration
• 8:30 AM · Morning warm-up presented by the YMCA of Greenville
• 8:40 AM · National Anthem and final call for the 1 Mile Walk
• 8:45 AM · 1 Mile Walk starts
• 9:00 AM · 5K Run/Walk starts
• 10:00 AM · 1/4 Mile Kids Fun Run starts on the field (heats by age, set by final registration numbers)
• 10:15 AM · Remarks and awards

All events start and finish at the Caine Halter Family YMCA.

• A T-shirt with your registration

Become a top fundraiser, or create or join a fundraising team today. Here's how to get started during registration:

• Go to the race page and select Sign Up.
• Enter the participant's information and select Continue.
• Select Become a Fundraiser.
• Create your individual fundraiser by entering a fundraiser name, your fundraising goal, and a message describing your fundraiser.
• Create or join a fundraising team. To create a team, enter the team name, fundraising goal and a message describing the team. To join a team, select an existing fundraising team.
• Choose a donation level if you would like to make a personal donation toward your fundraiser, and select who the donation is being made on behalf of.
• Select Continue and complete your race registration.

Thank you for helping us raise money, support those affected by cancer, and make a difference!